Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT1 | P42224 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30579311 | 0.84 | STAT1 (0.36) | STAT1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20558144 | 0.84 | STAT1 (0.36) | STAT1CYP11B2CYP11B1CYP17A1CYP3A4 | |
| SCHEMBL20542249 | 0.78 | CYP11B2 (0.36) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL30579302 | 0.78 | ALDH1A1 (0.37) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL20558056 | 0.78 | ALDH1A1 (0.37) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL30579319 | 0.78 | CYP11B2 (0.36) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL20541863 | 0.77 | CYP11B2 (0.40) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL30579378 | 0.77 | CYP11B2 (0.40) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL20542195 | 0.73 | KDM4E (0.37) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 | |
| SCHEMBL20542084 | 0.73 | CYP11B2 (0.36) | CYP11B2CYP11B1CYP17A1CYP3A4TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570138-B2 | Indole AHR inhibitors and uses thereof | KYN THERAPEUTICS (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570138-B2 | Indole AHR inhibitors and uses thereof | AHR, ARNT, IDO1 | STAT1 1152/4885CYP11B2 86/4885CYP11B1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.