Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | HINT1 | P49773 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.46 |
| ▸ | PNP | P00491 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714883 | 1.00 | HPGD (0.79) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL2583453 | 0.89 | HPGD (0.73) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL20149809 | 0.89 | HPGD (0.73) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL12740477 | 0.87 | HPGD (0.64) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL13834924 | 0.86 | HPGD (0.68) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL12714879 | 0.84 | NT5E (0.70) | HPGDNT5EP2RX3P2RX4P2RX7 | |
| SCHEMBL18769398 | 0.84 | HPGD (0.60) | HPGDHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL26135070 | 0.84 | HPGD (0.60) | HPGDHINT1TAAR1P2RX3P2RX4 | |
| SCHEMBL15747213 | 0.83 | P2RX3 (0.72) | HPGDNT5EP2RX3P2RX4P2RX7 | |
| SCHEMBL20850190 | 0.83 | P2RX3 (0.72) | HPGDNT5EP2RX3P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | MODERNATX, INC. (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570388-B2 | Phosphate replacement MRNA cap analogs | RNGTT, RNMT, CPSF6 | HPGD 3494/4885HINT1 525/4885GSK3A 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.