Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755839 | 0.87 | ERN1 (0.32) | ALDH1A1 | |
| SCHEMBL30078095 | 0.81 | KDM4E (0.42) | ALDH1A1 | |
| SCHEMBL15066126 | 0.81 | KDM4E (0.42) | ALDH1A1 | |
| SCHEMBL15065402 | 0.80 | PARP1 (0.39) | ALDH1A1 | |
| SCHEMBL21755836 | 0.79 | SYK (0.38) | ALDH1A1 | |
| SCHEMBL15065522 | 0.78 | SYK (0.40) | ALDH1A1 | |
| SCHEMBL30078023 | 0.78 | SYK (0.40) | ALDH1A1 | |
| SCHEMBL21755852 | 0.76 | EGLN1 (0.33) | ALDH1A1PDCD1CD274 | |
| SCHEMBL21755834 | 0.74 | ERN1 (0.32) | ALDH1A1 | |
| SCHEMBL21755806 | 0.74 | SYK (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797597-B1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |