Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | ERN1 | O75460 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21755834 | 0.88 | ERN1 (0.32) | ERN1ALDH1A1MAPT | |
| SCHEMBL21755847 | 0.83 | ERN1 (0.33) | GAAADORA2AERN1KDM4EMEN1 | |
| SCHEMBL21755806 | 0.83 | SYK (0.34) | ERN1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30078095 | 0.82 | KDM4E (0.42) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15066126 | 0.82 | KDM4E (0.42) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL15065402 | 0.81 | PARP1 (0.39) | ERN1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL21755845 | 0.80 | SGMS2 (0.32) | — | |
| SCHEMBL30078023 | 0.79 | SYK (0.40) | ERN1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15065522 | 0.79 | SYK (0.40) | ERN1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21755836 | 0.79 | SYK (0.38) | ERN1MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797597-B1 | SUBSTITUTED HETEROARYL ALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | GLOBAL BLOOD THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |