SCHEMBL21756089

SCHEMBL21756089

COc1cc(Cl)ccc1-c1c(C)cccc1F

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
KMT2A Q03164 3/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
CRHR1 P34998 1/20 0.39
ALDH1A1 P00352 4/20 0.39
PDE7A Q13946 2/20 0.39
KDM4E B2RXH2 1/20 0.38
TRPV4 Q9HBA0 1/20 0.37
TGFBR1 P36897 1/20 0.37
MEN1 O00255 2/20 0.37
CTSA P10619 2/20 0.37
HSD11B1 P28845 1/20 0.37
CNR1 P21554 1/20 0.37
RPS6KA2 Q15349 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21669067 0.91 KMT2A (0.43) HSP90AA1HSP90AB1KMT2ALMNAGAA
SCHEMBL21302781 0.88 ALDH1A1 (0.43) KMT2ALMNAGAAALDH1A1KDM4E
SCHEMBL24390457 0.86 KMT2A (0.44) HSP90AA1HSP90AB1KMT2ALMNAGAA
SCHEMBL19802986 0.84 KMT2A (0.39) HSP90AA1HSP90AB1KMT2ALMNAGAA
SCHEMBL4619485 0.82 MDM4 (0.42) KMT2ALMNAGAACRHR1ALDH1A1
SCHEMBL23740406 0.80 HSP90AA1 (0.43) HSP90AA1HSP90AB1KMT2ALMNAGAA
SCHEMBL21651103 0.80 ESR2 (0.40) HSP90AA1KMT2ALMNAALDH1A1KDM4E
SCHEMBL19802148 0.79 APP (0.47) HSP90AA1KMT2ALMNAALDH1A1KDM4E
SCHEMBL31186823 0.78 HSP90AA1 (0.44) HSP90AA1HSP90AB1KMT2ALMNAGAA
SCHEMBL21638971 0.78 HSP90AA1 (0.44) HSP90AA1HSP90AB1KMT2ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020040571-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2020-02-27 WO disclosed