SCHEMBL19802986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21669067	0.89	KMT2A (0.43)	KMT2ALMNAGAAHSP90AA1HSP90AB1
	SCHEMBL19802354	0.88	KMT2A (0.42)	KMT2ALMNAGAAALDH1A1MEN1
	SCHEMBL24390457	0.85	KMT2A (0.44)	KMT2ALMNAGAAHSP90AA1HSP90AB1
	SCHEMBL26287672	0.84	CYP1A1 (0.53)	KMT2AGAAALDH1A1MEN1CYP1A1
	SCHEMBL19802987	0.84	L3MBTL1 (0.43)	LMNAALDH1A1PDE7AMC4RCYP1A1
	SCHEMBL21756089	0.84	HSP90AA1 (0.46)	KMT2ALMNAGAAHSP90AA1HSP90AB1
	SCHEMBL21756057	0.81	HSP90AA1 (0.43)	KMT2ALMNAHSP90AA1HSP90AB1CTSA
	SCHEMBL17252479	0.80	ABCB1 (0.40)	PTGS1PTGS2CYP1A1CYP1A2CYP2E1
	SCHEMBL17241679	0.80	APP (0.46)	ALDH1A1KDM4E
	SCHEMBL20982342	0.78	CXCR2 (0.40)	KMT2AHSP90AA1ALDH1A1MEN1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.