Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3853118 | 0.98 | KDM4E (0.52) | KDM4ERXFP1LMNAMAPTALK | |
| SCHEMBL3846705 | 0.81 | LMNA (0.51) | KDM4ERXFP1LMNAMAPTALK | |
| SCHEMBL3845935 | 0.81 | HTT (0.56) | KDM4ERXFP1LMNAMAPTALK | |
| SCHEMBL29249633 | 0.81 | PARP1 (0.45) | KDM4EALKHTTALDH1A1TSHR | |
| SCHEMBL21816339 | 0.79 | L3MBTL1 (0.52) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL3845613 | 0.76 | IRAK4 (0.43) | KDM4ERXFP1LMNAMAPTALK | |
| SCHEMBL934881 | 0.74 | LMNA (0.58) | KDM4ELMNAMAPTALKHTT | |
| SCHEMBL2833079 | 0.74 | SMN1; SMN2 (0.52) | KDM4ELMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30902246 | 0.74 | SMN1; SMN2 (0.52) | KDM4ELMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL13621687 | 0.73 | RXFP1 (0.70) | KDM4ERXFP1LMNAMAPTALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041562-A1 | SUBSTITUTED IMIDAZOLES FOR THE INHIBITION OF TGF-BETA AND METHODS OF TREATMENT | CLAVIUS PHARMACEUTICALS, LLC (US) | 2020-02-27 | — | — | WO | disclosed |