Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 10/20 | 1.00 |
| ▸ | ACHE | P22303 | 4/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2124625 | 0.98 | METAP1 (1.00) | METAP1ACHE | |
| Hydrochloric Acid SCHEMBL30772482 | 0.98 | METAP1 (1.00) | METAP1ACHE | |
| SCHEMBL8003063 | 0.83 | METAP1 (0.71) | METAP1ACHECYP19A1 | |
| SCHEMBL6271181 | 0.83 | METAP1 (0.71) | METAP1ACHECYP19A1 | |
| SCHEMBL2125675 | 0.83 | METAP1 (0.71) | METAP1ACHECYP19A1 | |
| SCHEMBL6270614 | 0.83 | METAP1 (0.71) | METAP1ACHECYP19A1 | |
| SCHEMBL14181702 | 0.83 | METAP1 (0.73) | METAP1ACHECYP19A1 | |
| Hydrochloric Acid SCHEMBL2125507 | 0.82 | METAP1 (0.72) | METAP1CYP19A1 | |
| Bromide SCHEMBL9065521 | 0.82 | METAP1 (0.71) | METAP1ACHECYP19A1 | |
| SCHEMBL3822940 | 0.81 | METAP1 (0.68) | METAP1ACHECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889615-B2 | Methods for promoting epithelialization and healing of chronic wounds | NEW YORK UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |
| US-8883839-B2 | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBOTT LABORATORIES (US) | 2014-11-11 | — | — | US | disclosed |
| US-20120289463-A1 | Compositions and Methods for Promoting Epithelialization and Wound Closure | NEW YORK UNIVERSITY (US) | 2012-11-15 | — | — | US | disclosed |
| US-20120040947-A1 | TETRALINE AND INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBOTT LABORATORIES (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2011082231-A1 | COMPOSITIONS AND METHODS FOR PROMOTING EPITHELIALIZATION AND WOUND CLOSURE | NEW YORK UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| US-6054286-A | DETECTING MODULATORS OF IMMUNE RESPONSE; INCUBATION OF PROTEIN KINASE C WITH MODULATOR AND ASCERTAINING PRESENCE OF MODULATING ACTIVITY | TELIK, INC. (US) | 2000-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120289463-A1 | Compositions and Methods for Promoting Epithelialization and Wound Closure | GSK3B, GSK3A, GSKIP | METAP1 1231/4885ACHE 2786/4885CYP19A1 4583/4885 |
| US-20120040947-A1 | TETRALINE AND INDANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | SLC10A1, SUGT1, SLC10A2 | METAP1 324/4885ACHE 1221/4885CYP19A1 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.