Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21757283 | 0.80 | MEN1 (0.34) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL21060996 | 0.77 | DEGS1 (0.39) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL22663851 | 0.72 | ALDH1A1 (0.43) | KMT2AMEN1DEGS1ALDH1A1MAPT | |
| SCHEMBL8129608 | 0.72 | NR4A2 (0.46) | KMT2AMEN1DEGS1ALDH1A1MAPT | |
| SCHEMBL31599571 | 0.71 | PDE4A (0.49) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL5168262 | 0.71 | PDE4A (0.49) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL8548467 | 0.71 | PDE4A (0.49) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL7759160 | 0.71 | KDM1A (0.38) | KMT2AMEN1DEGS1KDM1AALDH1A1 | |
| SCHEMBL28691456 | 0.71 | KMT2A (0.41) | KMT2AMEN1KDM1AALDH1A1MAPT | |
| SCHEMBL17148268 | 0.69 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613734-A2 | PROCESS FOR PRODUCING PYRROLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-02-26 | — | — | EP | disclosed |