Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL21462500 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL19471869 | 0.89 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL670068 | 0.89 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL305984 | 0.89 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL9468123 | 0.88 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL9468126 | 0.88 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| Hydrochloric Acid SCHEMBL11318740 | 0.88 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL9468108 | 0.88 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1MAPTRAB9AMAPK1 | |
| SCHEMBL1536443 | 0.84 | NR4A2 (0.60) | NR4A2NR4A1NR4A3SMN1; SMN2ALDH1A1 | |
| SCHEMBL582234 | 0.84 | NR4A2 (0.60) | NR4A2NR4A1NR4A3SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1049682-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | Versicor, Inc. (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |