Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5168262 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL8548467 | 1.00 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL11753040 | 0.88 | SMN1; SMN2 (0.48) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL625933 | 0.80 | GABRA1 (0.53) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL625934 | 0.80 | GABRA1 (0.53) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL9644205 | 0.80 | GABRA1 (0.42) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL9645499 | 0.80 | GABRA1 (0.42) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL625935 | 0.80 | GABRA1 (0.53) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL25342763 | 0.78 | GABRA1 (0.58) | PDE4APDE4BPDE4CPDE4DGABRA1 | |
| SCHEMBL11761840 | 0.78 | GABRA1 (0.58) | PDE4APDE4BPDE4CPDE4DGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077035-A | As CX32,4, 6-Trisubstituted 1,3, 5-triazines as modulators of CR1 | 阿斯利康(瑞典)有限公司 | 2025-05-30 | — | — | CN | disclosed |