Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23586513 | 0.86 | THRB (0.43) | THRBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL19122375 | 0.80 | ALDH1A1 (0.38) | THRBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31643870 | 0.76 | CA2 (0.43) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL258754 | 0.76 | CA2 (0.43) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL941531 | 0.76 | KMT2A (0.45) | THRBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL6977984 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2MAPTHPGDHSD17B10 | |
| SCHEMBL6981102 | 0.75 | BPTF (0.36) | THRBALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL25328991 | 0.75 | ALDH1A1 (0.45) | THRBALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL12440994 | 0.75 | MAPT (0.51) | THRBALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL11134220 | 0.75 | THRB (0.41) | THRBALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038464-A1 | FIBRIC ACID COMPOUND AND MEDICAL USE THEREOF | 北京厚燊药德科技有限责任公司 | 2020-02-27 | — | — | WO | disclosed |