SCHEMBL21757559

SCHEMBL21757559

CNC1CCC2(CCCCO2)C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2743248 0.84 PRMT1 (0.32) PRMT1
SCHEMBL18361888 0.80
SCHEMBL18792822 0.76
SCHEMBL21757622 0.73 ADH1B (0.42)
SCHEMBL10368695 0.71 OPRK1 (0.30)
SCHEMBL10366864 0.71 OPRK1 (0.30)
SCHEMBL6341442 0.71 ALDH1A1 (0.38)
SCHEMBL18576891 0.71 CYP1A2 (0.35)
SCHEMBL18576605 0.71 CYP1A2 (0.35)
SCHEMBL18573248 0.71 CYP1A2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3215509-B1 SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS LYSOSOMAL THERAPEUTICS INC (US) 2020-02-26 EP disclosed