Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630948 | 0.84 | EGFR (0.33) | JAK2BTKEGFR | |
| SCHEMBL18149237 | 0.84 | EGFR (0.33) | JAK2BTKEGFR | |
| SCHEMBL12456123 | 0.82 | UHRF1 (0.35) | IRAK4 | |
| SCHEMBL29781537 | 0.82 | UHRF1 (0.35) | IRAK4 | |
| SCHEMBL16042893 | 0.81 | NOS3 (0.33) | JAK2BTKEGFR | |
| SCHEMBL16043086 | 0.81 | EGFR (0.36) | JAK2BTKEGFR | |
| SCHEMBL16754480 | 0.79 | LPL (0.35) | JAK2BTKEGFRIRAK4 | |
| SCHEMBL30606435 | 0.79 | EGFR (0.37) | EGFRUCHL1 | |
| SCHEMBL26658292 | 0.79 | EGFR (0.37) | EGFRUCHL1 | |
| SCHEMBL29977691 | 0.79 | UHRF1 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613737-A1 | NOVEL INHIBITOR OF CYCLIN-DEPENDENT KINASE CDK9 | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2020-02-26 | — | — | EP | disclosed |