Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | LPL | P06858 | 1/20 | 0.30 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18149237 | 1.00 | EGFR (0.33) | EGFRJAK2BTKLPLLIPG | |
| SCHEMBL18225077 | 0.86 | EGFR (0.33) | EGFRJAK2BTKLPLLIPG | |
| SCHEMBL21757580 | 0.84 | JAK2 (0.33) | EGFRJAK2BTK | |
| SCHEMBL15342466 | 0.84 | EGFR (0.31) | EGFRJAK2BTK | |
| SCHEMBL16042893 | 0.83 | NOS3 (0.33) | EGFRJAK2BTK | |
| SCHEMBL16043086 | 0.83 | EGFR (0.36) | EGFRJAK2BTKLPLLIPG | |
| SCHEMBL15342469 | 0.83 | EGFR (0.36) | EGFRJAK2BTKLPLLIPG | |
| SCHEMBL14245043 | 0.81 | CHRNB2 (0.31) | EGFRJAK2BTK | |
| SCHEMBL29276892 | 0.80 | EGFR (0.43) | EGFR | |
| SCHEMBL30606435 | 0.80 | EGFR (0.37) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |