Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.34 |
| ▸ | WNT3A | P56704 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118801 | 0.88 | MAOA (0.45) | MAOAMAOBTSHRERCC5FEN1 | |
| SCHEMBL23982058 | 0.79 | MEN1 (0.41) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL26261196 | 0.79 | CTNNB1 (0.51) | ERCC5FEN1CTNNB1WNT3AHPGD | |
| SCHEMBL13067921 | 0.77 | ALDH1A1 (0.30) | TSHRKDM4EGAA | |
| SCHEMBL7197694 | 0.77 | MAOA (0.55) | MAOAMAOBTSHRERCC5FEN1 | |
| SCHEMBL15966565 | 0.77 | MAOA (0.59) | MAOAMAOBTSHRERCC5FEN1 | |
| SCHEMBL21758830 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL7193411 | 0.74 | MAOA (0.51) | MAOAMAOBTSHRERCC5FEN1 | |
| SCHEMBL21758828 | 0.73 | MAOA (0.44) | MAOAMAOBKMT2AMAPK1 | |
| SCHEMBL25137479 | 0.73 | MAOA (0.50) | MAOAMAOBERCC5FEN1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |