Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982058 | 0.76 | MEN1 (0.41) | ALDH1A1 | |
| SCHEMBL21758653 | 0.76 | MAOA (0.49) | — | |
| SCHEMBL13067921 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7574908 | 0.75 | MEN1 (0.36) | ALDH1A1 | |
| SCHEMBL9715778 | 0.73 | LMNA (0.37) | ALDH1A1 | |
| SCHEMBL22758504 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL536537 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL8195694 | 0.73 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2874493 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL21758828 | 0.71 | MAOA (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221760-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS | NORTHWESTERN UNIVERSITY (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |