Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | UNG | P13051 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23981717 | 0.86 | UNG (0.47) | MEN1KMT2AALDH1A1UNG | |
| SCHEMBL21758828 | 0.76 | MAOA (0.44) | KMT2AALDH1A1 | |
| SCHEMBL19621066 | 0.75 | TP53 (0.42) | TP53TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL14992845 | 0.75 | TDP1 (0.47) | TP53TDP1MEN1KMT2AALDH1A1 | |
| Styrene SCHEMBL11314880 | 0.71 | ALDH1A1 (0.47) | TP53TDP1ALDH1A1TSHR | |
| SCHEMBL17529236 | 0.70 | TP53 (0.48) | TP53TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL21758843 | 0.69 | MEN1 (0.30) | TDP1MEN1KMT2A | |
| SCHEMBL28236456 | 0.69 | TDP1 (0.47) | TP53TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12449053 | 0.69 | TP53 (0.47) | TP53TDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL12449046 | 0.69 | TP53 (0.47) | TP53TDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |