Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758846 | 0.80 | CYP19A1 (0.41) | — | |
| SCHEMBL24633879 | 0.77 | PDE4A (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL21758757 | 0.73 | GSK3B (0.43) | MEN1KMT2A | |
| SCHEMBL21758849 | 0.73 | ALDH1A1 (0.37) | MEN1KMT2ATDP1 | |
| SCHEMBL23963002 | 0.72 | PDE4A (0.39) | MEN1KMT2ATDP1 | |
| SCHEMBL21758828 | 0.72 | MAOA (0.44) | KMT2A | |
| SCHEMBL21758845 | 0.70 | CTSL (0.35) | — | |
| SCHEMBL21758833 | 0.69 | ALDH1A1 (0.38) | MEN1KMT2A | |
| SCHEMBL21758759 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL21758848 | 0.69 | LOXL2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |