Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570765 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL13698339 | 0.68 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL6418003 | 0.66 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL14470983 | 0.62 | KDM4E (0.38) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL15128265 | 0.61 | — | — | |
| SCHEMBL13941293 | 0.61 | KDM4E (0.37) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL21655004 | 0.61 | KDM4E (0.40) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL15057332 | 0.60 | — | — | |
| SCHEMBL6422433 | 0.60 | KDM4E (0.36) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL21759408 | 0.60 | KDM4E (0.33) | KDM4EALDH1A1POLBHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585462-B1 | FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS | TAKEDA PHARMACEUTICALS CO (JP) | 2020-02-26 | — | — | EP | disclosed |