Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418006 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL6418003 | 0.70 | ALDH1A1 (0.41) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL13941293 | 0.65 | KDM4E (0.37) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL21655004 | 0.65 | KDM4E (0.40) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL4570765 | 0.63 | KDM4E (0.47) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL3440245 | 0.63 | KDM4E (0.38) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL588122 | 0.60 | OPRM1 (0.46) | KDM4EALDH1A1POLBOPRM1OPRL1 | |
| SCHEMBL13698339 | 0.60 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL21759296 | 0.60 | KDM4E (0.44) | KDM4EALDH1A1POLBHPGDHSD17B10 | |
| SCHEMBL23148740 | 0.58 | OPRM1 (0.43) | KDM4EALDH1A1OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | WASHINGTON UNIVERSITY | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256150-A1 | Enantioselective acyl transfer catalysts and their use in kinetic resolution of alcohols and desymmetrization of meso-diols | ADH5, DBI, ADH1A | KDM4E 2445/4885ALDH1A1 203/4885POLB 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.