Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647439 | 0.83 | NPSR1 (0.38) | NPSR1MAPTRXFP1PARP1NR3C1 | |
| SCHEMBL29469917 | 0.83 | NPSR1 (0.36) | NPSR1MAPTRXFP1PARP1NR3C1 | |
| SCHEMBL30016297 | 0.83 | PARP1 (0.37) | NPSR1MAPTRXFP1CYP2A6PARP1 | |
| SCHEMBL743679 | 0.83 | NPSR1 (0.36) | NPSR1MAPTRXFP1PARP1NR3C1 | |
| SCHEMBL16142977 | 0.80 | MAPT (0.37) | NPSR1MAPTRXFP1PARP1NR3C1 | |
| SCHEMBL21761112 | 0.78 | NR3C1 (0.37) | NPSR1MAPTRXFP1PARP1NR3C1 | |
| SCHEMBL12326401 | 0.73 | LMNA (0.33) | MAPTWDR5 | |
| SCHEMBL31394015 | 0.73 | MAPT (0.36) | NPSR1MAPTRXFP1CYP2A6PARP1 | |
| SCHEMBL6342164 | 0.73 | MAPT (0.36) | NPSR1MAPTRXFP1CYP2A6PARP1 | |
| SCHEMBL17007465 | 0.73 | DHCR7 (0.47) | NPSR1RECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |