Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760689 | 0.85 | CA2 (0.35) | KDM1ANOTUMMAPTPOLB | |
| SCHEMBL15821770 | 0.83 | KDM1A (0.36) | KDM1APOLB | |
| SCHEMBL21761049 | 0.78 | CCR2 (0.38) | KDM1ANOTUMPOLB | |
| SCHEMBL21761023 | 0.77 | — | — | |
| SCHEMBL14994081 | 0.76 | KDM1A (0.38) | KDM1APTGDR2 | |
| SCHEMBL21761046 | 0.75 | SMN1; SMN2 (0.39) | PTGDR2MAPT | |
| SCHEMBL21761024 | 0.75 | MAOB (0.41) | MAPT | |
| SCHEMBL21760572 | 0.73 | POLB (0.43) | PTGS2MAPTPOLB | |
| SCHEMBL21761100 | 0.72 | RXFP1 (0.44) | MAPTPOLB | |
| SCHEMBL21761047 | 0.71 | KDM1A (0.38) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |