Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548708 | 0.90 | MAPT (0.74) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16655629 | 0.86 | MAPT (0.45) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16654009 | 0.85 | TP53 (0.55) | MAPTKMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2927491 | 0.82 | GAA (0.55) | MAPTALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL22652221 | 0.81 | L3MBTL1 (0.51) | MAPTKMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL16654429 | 0.81 | GAA (0.61) | MAPTALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL28404646 | 0.81 | LMNA (0.45) | MAPTKMT2AALDH1A1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL28515207 | 0.80 | GAA (0.59) | MAPTALDH1A1HPGDMAPK1L3MBTL1 | |
| SCHEMBL16653873 | 0.80 | TP53 (0.47) | MAPTKMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28610614 | 0.80 | LMNA (0.42) | MAPTKMT2AALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038458-A1 | CLASS OF FUSED RING TRIAZOLE COMPOUND, PREPARATION METHOD, AND USE | 如东凌达生物医药科技有限公司 | 2020-02-27 | — | — | WO | disclosed |