SCHEMBL21761995

SCHEMBL21761995

CCS(=O)(=O)c1cc(C(=O)N=S(C)(C)=O)cnc1-n1cc2ncc(C(F)(F)F)cc2n1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 3/20 0.33
SCN10A Q9Y5Y9 1/20 0.33
DDR1 Q08345 7/20 0.33
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
PDGFRB P09619 2/20 0.31
KDR P35968 2/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
EIF2AK2 P19525 1/20 0.30
PPARD Q03181 1/20 0.30
POLB P06746 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21750104 0.82 EGLN1 (0.35) EGLN1DDR1
SCHEMBL20325639 0.78 GRIN2B (0.37) SCN10ADDR1
SCHEMBL21750100 0.77 EGLN1 (0.34) EGLN1DDR1
SCHEMBL20326612 0.76 GRIN2B (0.39) DDR1
SCHEMBL21750103 0.76 EGLN1 (0.36) EGLN1DDR1
SCHEMBL21750120 0.74 POLB (0.44) EGLN1DDR1MEN1KMT2APDGFRB
SCHEMBL30989744 0.73 PTGS1 (0.35) SCN10ADDR1LMNASMN1; SMN2PPARD
SCHEMBL25885649 0.73 PTGS1 (0.35) SCN10ADDR1LMNASMN1; SMN2PPARD
SCHEMBL25887333 0.73 DDR1 (0.34) DDR1
SCHEMBL17504810 0.71 DDR1 (0.36) EGLN1SCN10ADDR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10894792-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2021-01-19 US disclosed
US-20200062755-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (IN) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062755-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, SQOR EGLN1 3702/4885SCN10A 1193/4885DDR1 4585/4885
US-10894792-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents DDT, ACHE, SQOR EGLN1 3702/4885SCN10A 1193/4885DDR1 4585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.