Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 9/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20326612 | 0.92 | GRIN2B (0.39) | GRIN2BDDR1GRIN1PKMPTGS2 | |
| SCHEMBL20325638 | 0.86 | DDR1 (0.42) | GRIN2BDDR1PTGS1 | |
| SCHEMBL30989744 | 0.83 | PTGS1 (0.35) | GRIN2BDDR1GRIN1PKMSCN10A | |
| SCHEMBL25885649 | 0.83 | PTGS1 (0.35) | GRIN2BDDR1GRIN1PKMSCN10A | |
| SCHEMBL20326611 | 0.81 | DDR1 (0.41) | GRIN2BDDR1GRIN1PTGS2PTGS1 | |
| SCHEMBL21761995 | 0.78 | EGLN1 (0.33) | DDR1SCN10A | |
| SCHEMBL25885996 | 0.76 | — | — | |
| SCHEMBL25887333 | 0.76 | DDR1 (0.34) | DDR1 | |
| SCHEMBL23014161 | 0.74 | DDR1 (0.35) | GRIN2BDDR1GRIN1PKM | |
| SCHEMBL17504810 | 0.73 | DDR1 (0.36) | DDR1PKMSCN10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-02 | — | — | US | disclosed |
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-02 | — | — | US | disclosed |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-24 | — | — | US | disclosed |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-24 | — | — | US | disclosed |
| WO-2018113900-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10667518-B2 | Pesticidally active heterocyclic derivatives with sulphur containing substituents | DDT, ACHE, GSTM1 | GRIN2B 792/4885DDR1 4516/4885GRIN1 457/4885 |
| US-20200253210-A1 | Pesticidally Active Heterocyclic Derivatives With Sulphur Containing Substituents | DDT, ACHE, GSTM1 | GRIN2B 792/4885DDR1 4516/4885GRIN1 457/4885 |
| US-20190320657-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | DDT, ACHE, GSTM1 | GRIN2B 792/4885DDR1 4516/4885GRIN1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.