Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2818137 | 0.94 | L3MBTL1 (0.46) | L3MBTL1BACE1ADRB2ADRB1ADRB3 | |
| SCHEMBL2177713 | 0.84 | BACE1 (0.44) | BACE1IDO1CTSSHTT | |
| SCHEMBL2202484 | 0.84 | L3MBTL1 (0.44) | L3MBTL1ADRB2ADRB1ADRB3PPARA | |
| SCHEMBL2207432 | 0.83 | BCHE (0.43) | L3MBTL1ADRB2ADRB1ADRB3PPARA | |
| SCHEMBL2158118 | 0.83 | SIGMAR1 (0.43) | BACE1IDO1MAPTCTSS | |
| SCHEMBL2178099 | 0.81 | IDO1 (0.42) | BACE1IDO1CTSSHTTSYK | |
| SCHEMBL3138728 | 0.77 | L3MBTL1 (0.48) | L3MBTL1PPARAIDO1MAPTCTSS | |
| SCHEMBL2818140 | 0.77 | L3MBTL1 (0.50) | L3MBTL1PPARAMAPTCTSS | |
| SCHEMBL30958382 | 0.77 | L3MBTL1 (0.60) | L3MBTL1PPARAIDO1MAPTCTSS | |
| SCHEMBL2167444 | 0.77 | EPHX1 (0.36) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340242-A2 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2011-07-06 | — | — | EP | disclosed |