Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2178104 | 0.84 | CTSK (0.46) | PPARAPPARGCTSSCTSK | |
| SCHEMBL2177717 | 0.81 | CTSK (0.45) | PPARAPPARGCTSSCTSK | |
| SCHEMBL2818137 | 0.81 | L3MBTL1 (0.46) | L3MBTL1PPARACTSSMAPT | |
| SCHEMBL2821042 | 0.78 | CTSK (0.40) | CTSSCTSK | |
| SCHEMBL3138728 | 0.78 | L3MBTL1 (0.48) | L3MBTL1PPARAPPARGCTSSMAPT | |
| SCHEMBL2176308 | 0.77 | L3MBTL1 (0.50) | L3MBTL1PPARACTSSMAPT | |
| SCHEMBL28108976 | 0.74 | CTSK (0.62) | PPARAPPARGCTSSCTSK | |
| SCHEMBL27730329 | 0.74 | CTSK (0.62) | PPARAPPARGCTSSCTSK | |
| SCHEMBL22042132 | 0.74 | CTSK (0.62) | PPARAPPARGCTSSCTSK | |
| SCHEMBL8615711 | 0.71 | PPARA (0.69) | L3MBTL1PPARAPPARGCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048332-A2 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-29 | — | — | WO | disclosed |