Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13895331 | 0.82 | PAOX (0.45) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL18023622 | 0.82 | PAOX (0.42) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL24183277 | 0.80 | LMNA (0.45) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL23086022 | 0.79 | CHRNB2 (0.33) | ALDH1A1CHRNB2CHRNB4CHRNA4HDAC1 | |
| SCHEMBL8297270 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL17031405 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL13895336 | 0.76 | CYP1A2 (0.42) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL26742537 | 0.76 | PAOX (0.40) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL8356812 | 0.76 | PAOX (0.56) | PAOXMEN1ALDH1A1PLGLMNA | |
| SCHEMBL2979864 | 0.76 | PAOX (0.56) | PAOXMEN1ALDH1A1PLGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134127-B1 | ANTIBODY-DRUG CONJUGATES WITH HIGH DRUG LOADING | RINAT NEUROSCIENCE CORP (US) | 2020-02-26 | — | — | EP | disclosed |