SCHEMBL21765348

SCHEMBL21765348

CC(C)c1ccc(I)cc1C1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
GABRB2 P47870 1/20 0.34
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21769671 0.83 TSHR (0.33)
SCHEMBL21756929 0.78 GABRA1 (0.36) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL6276897 0.77 TSHR (0.41) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL19729054 0.73 LTB4R (0.37) GABRA1GABRB2CA1CA2
SCHEMBL17865232 0.73 HTR2B (0.41)
SCHEMBL12197671 0.69 GABRA1 (0.52) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL21756921 0.69
SCHEMBL16860570 0.68 GABRA1 (0.44) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL12224190 0.66 GABRA1 (0.43) GABRA1GABRB1GABRB2
SCHEMBL21756935 0.65 LMNA (0.59) GABRA1GABRB1GABRB2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020039094-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERATIVE ACTIVITY Xeniopro GmbH (DE) 2020-02-27 WO disclosed