Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21058167 | 0.81 | LMNA (0.37) | — | |
| SCHEMBL30685975 | 0.81 | LMNA (0.37) | — | |
| SCHEMBL18554888 | 0.77 | NOS3 (0.35) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL30052259 | 0.77 | NOS3 (0.35) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL19083212 | 0.77 | TERT (0.34) | — | |
| SCHEMBL14036990 | 0.77 | TDP1 (0.46) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL4331730 | 0.77 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL21752363 | 0.76 | NOS3 (0.34) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL23888235 | 0.75 | NQO2 (0.35) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL29869252 | 0.75 | NQO2 (0.35) | TDP1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2020041301-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |