Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037837 | 0.89 | NOTUM (0.55) | TSHRRAB9ATDP1NOTUMNPC1 | |
| SCHEMBL1040074 | 0.82 | NOTUM (0.51) | TSHRRAB9ANOTUMNPC1GAA | |
| SCHEMBL15004187 | 0.81 | TSHR (0.69) | TSHRRAB9ANPC1GAAMEN1 | |
| SCHEMBL21765906 | 0.79 | NPC1 (0.35) | TSHRRAB9ATDP1NOTUMNPC1 | |
| SCHEMBL222437 | 0.79 | TDP1 (0.69) | TSHRRAB9ATDP1NPC1MEN1 | |
| SCHEMBL29518679 | 0.79 | TSHR (0.46) | TSHRRAB9ATDP1NPC1KMT2A | |
| SCHEMBL1866130 | 0.79 | TSHR (0.46) | TSHRRAB9ATDP1NPC1KMT2A | |
| SCHEMBL839206 | 0.79 | RAB9A (0.66) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16230884 | 0.79 | TSHR (0.46) | TSHRRAB9ATDP1NPC1MEN1 | |
| SCHEMBL21589400 | 0.75 | USP30 (0.54) | TSHRRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |