Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765658 | 0.79 | TSHR (0.43) | NPC1TSHRNOTUMRAB9ATDP1 | |
| SCHEMBL1037837 | 0.70 | NOTUM (0.55) | NPC1TSHRNOTUMRAB9ATDP1 | |
| SCHEMBL1040074 | 0.65 | NOTUM (0.51) | NPC1TSHRNOTUMRAB9A | |
| SCHEMBL15004187 | 0.64 | TSHR (0.69) | NPC1TSHRRAB9A | |
| SCHEMBL222437 | 0.63 | TDP1 (0.69) | NPC1TSHRRAB9ATDP1 | |
| SCHEMBL29518679 | 0.63 | TSHR (0.46) | NPC1TSHRRAB9ATDP1 | |
| SCHEMBL1866130 | 0.63 | TSHR (0.46) | NPC1TSHRRAB9ATDP1 | |
| SCHEMBL839206 | 0.63 | RAB9A (0.66) | NPC1RAB9A | |
| SCHEMBL16230884 | 0.63 | TSHR (0.46) | NPC1TSHRRAB9ATDP1 | |
| SCHEMBL21589400 | 0.60 | USP30 (0.54) | NPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |