Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12706078 | 0.78 | MAOA (0.44) | MAOAMAOBSLC6A4 | |
| SCHEMBL21765697 | 0.78 | NOTUM (0.52) | NOTUMCYP1A2TDP1HRH3NAMPT | |
| SCHEMBL16284216 | 0.75 | ABHD6 (0.55) | NOTUMHRH3MAOAMAOBSLC6A4 | |
| SCHEMBL9601675 | 0.74 | NOTUM (0.52) | NOTUMTDP1HRH3ABHD6MEN1 | |
| SCHEMBL16284191 | 0.74 | NOTUM (0.52) | NOTUMCYP1A2TDP1MEN1KMT2A | |
| SCHEMBL16284189 | 0.74 | NOTUM (0.52) | NOTUMCYP1A2 | |
| SCHEMBL10150901 | 0.74 | NOTUM (0.62) | NOTUMHDAC8HDAC6NAMPTDPP4 | |
| SCHEMBL14067114 | 0.74 | NOTUM (0.62) | NOTUMMAOBHDAC8HDAC6ABHD6 | |
| SCHEMBL1197829 | 0.73 | NOTUM (1.00) | NOTUMHRH3HDAC8NAMPTDPP4 | |
| SCHEMBL16101941 | 0.72 | NOTUM (0.60) | NOTUMHDAC8HDAC6NAMPTABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |