Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593768 | 0.82 | TNFSF11 (0.44) | KDM4EPOLBMAPTTNFSF11ALDH1A1 | |
| SCHEMBL16284216 | 0.82 | ABHD6 (0.55) | NOTUMKDM4EMAPTALDH1A1GAA | |
| Bromide SCHEMBL9870594 | 0.81 | MAOA (0.44) | KDM4EPOLBMAPTTNFSF11ALDH1A1 | |
| SCHEMBL9826524 | 0.75 | MAOA (0.62) | TSHRMAPK1TDP1L3MBTL1MEN1 | |
| SCHEMBL17197346 | 0.75 | NOTUM (0.46) | NOTUMKDM4EPOLBALDH1A1GAA | |
| SCHEMBL7277197 | 0.74 | NOTUM (0.53) | NOTUMKDM4EABHD6CA9HRH3 | |
| SCHEMBL16715040 | 0.74 | PGR (0.49) | KDM4EPOLBMAPTTNFSF11ALDH1A1 | |
| SCHEMBL21765692 | 0.74 | NOTUM (0.57) | NOTUMABHD6TDP1MEN1KMT2A | |
| SCHEMBL6275593 | 0.73 | TNFSF11 (0.67) | KDM4EMAPTTNFSF11ALDH1A1GAA | |
| SCHEMBL9202003 | 0.72 | KDM4E (0.46) | KDM4EPOLBMAPTTNFSF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227986-B1 | ISOINDOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |