Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577300 | 0.96 | CYP3A4 (0.58) | CYP3A4ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL17680989 | 0.83 | KMT2A (0.77) | CYP3A4ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11578349 | 0.83 | HPGD (0.65) | CYP3A4ALDH1A1SMN1; SMN2NPC1HPGD | |
| SCHEMBL30116158 | 0.81 | ALDH1A1 (0.56) | CYP3A4ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL20597334 | 0.81 | ALDH1A1 (0.56) | CYP3A4ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL12900894 | 0.81 | ALDH1A1 (0.56) | CYP3A4ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL2914539 | 0.81 | ALDH1A1 (0.54) | CYP3A4ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9833934 | 0.80 | CYP3A4 (0.46) | CYP3A4ALDH1A1SMN1; SMN2NPC1TP53 | |
| SCHEMBL11691270 | 0.79 | HTT (0.52) | ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E | |
| SCHEMBL15434035 | 0.79 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041270-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | FOG PHARMACEUTICALS, INC. (US) | 2020-02-27 | — | — | WO | disclosed |