Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MITF | O75030 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159119 | 0.84 | SMN1; SMN2 (0.47) | POLBMITFKMT2AMAPTTP53 | |
| SCHEMBL23158968 | 0.84 | MAPT (0.49) | POLBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL21766162 | 0.84 | ALDH1A1 (0.51) | POLBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL23158997 | 0.83 | ALDH1A1 (0.50) | MAPTHPGD | |
| SCHEMBL23159144 | 0.83 | KMT2A (0.49) | POLBKMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL23158963 | 0.81 | MITF (0.43) | MITFKMT2AMAPTSMN1; SMN2HPGD | |
| SCHEMBL23159065 | 0.80 | NPC1 (0.44) | MITFKMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL23159006 | 0.80 | KMT2A (0.44) | POLBMITFKMT2AMAPTHPGD | |
| SCHEMBL23159005 | 0.80 | KMT2A (0.44) | POLBMITFKMT2AMAPTHPGD | |
| SCHEMBL23158962 | 0.79 | KMT2A (0.40) | POLBMITFKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854797-A1 | CRYSTAL FORM OF TRI-CYCLE COMPOUND AND APPLICATION THEREOF | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |
| WO-2020038456-A1 | CRYSTAL FORM OF TRI-CYCLE COMPOUND AND APPLICATION THEREOF | 福建广生堂药业股份有限公司 | 2020-02-27 | — | — | WO | disclosed |