Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FGB | P02675 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23159119 | 0.86 | SMN1; SMN2 (0.47) | ALDH1A1LMNAHTTALOX15POLB | |
| SCHEMBL21766095 | 0.84 | POLB (0.44) | POLBTP53TDP1SMN1; SMN2RXFP1 | |
| SCHEMBL23159144 | 0.78 | KMT2A (0.49) | ALDH1A1LMNAPOLBTP53SMN1; SMN2 | |
| SCHEMBL22301309 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTALOX15POLB | |
| SCHEMBL23158968 | 0.76 | MAPT (0.49) | ALDH1A1POLBTP53SMN1; SMN2MAPT | |
| SCHEMBL19984532 | 0.75 | ALDH1A1 (0.58) | ALDH1A1LMNAHTTALOX15POLB | |
| SCHEMBL23158963 | 0.74 | MITF (0.43) | ALDH1A1LMNAHTTBLMSMN1; SMN2 | |
| SCHEMBL23158997 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHTTBLML3MBTL1 | |
| SCHEMBL23159005 | 0.74 | KMT2A (0.44) | ALDH1A1HTTPOLBMAPTHPGD | |
| SCHEMBL23159065 | 0.74 | NPC1 (0.44) | ALDH1A1SMN1; SMN2HSD17B10HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038456-A1 | CRYSTAL FORM OF TRI-CYCLE COMPOUND AND APPLICATION THEREOF | 福建广生堂药业股份有限公司 | 2020-02-27 | — | — | WO | disclosed |