Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347631 | 0.85 | CASP2 (0.44) | PSMB5HDAC8HDAC6FAAHHDAC1 | |
| SCHEMBL16472474 | 0.85 | HDAC7 (0.34) | MEN1KMT2AHDAC7HDAC8HDAC6 | |
| SCHEMBL19661531 | 0.83 | MEN1 (0.40) | MEN1KMT2APSMB5HTR2CDRD3 | |
| SCHEMBL19455924 | 0.83 | MEN1 (0.40) | MEN1KMT2APSMB5HTR2CDRD3 | |
| SCHEMBL3692879 | 0.82 | MEN1 (0.46) | MEN1KMT2APSMB5CYP2C9ALDH1A1 | |
| SCHEMBL12713499 | 0.82 | PTPN1 (0.44) | MEN1KMT2APSMB5GPR84FAAH | |
| SCHEMBL24371945 | 0.80 | PAOX (0.38) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL3684729 | 0.80 | CYP2D6 (0.50) | HDAC7HDAC8HDAC6HDAC9HDAC5 | |
| SCHEMBL15943619 | 0.80 | MEN1 (0.44) | MEN1KMT2APSMB5HTR2CDRD3 | |
| SCHEMBL21766673 | 0.80 | MEN1 (0.44) | MEN1KMT2APSMB5HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | KYOWA KIRIN CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
| EP-3670514-A1 | PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS | Genentech, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2017092691-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | THE UNIVERSITY OF HONG KONG (CN) | 2017-06-08 | — | — | WO | disclosed |
| US-20170152286-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | THE UNIVERSITY OF HONG KONG (HK) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | NSUN3, NSUN2, RNASEH1 | MEN1 1500/4885KMT2A 1750/4885PSMB5 3144/4885 |
| US-20170152286-A1 | STAPLED HELICAL PEPTIDES AND METHODS OF SYNTHESIS | SPPL2B, SUCLA2, PRAP1 | MEN1 1283/4885KMT2A 3833/4885PSMB5 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.