SCHEMBL21766769

SCHEMBL21766769

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nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SYK P43405 1/20 0.41
▸ IL23R Q5VWK5 13/20 0.39
▸ GLP1R P43220 4/20 0.38
▸ SCTR P47872 1/20 0.38
▸ SLC40A1 Q9NP59 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21766783 0.89 SYK (0.47) SYKIL23RGLP1RSCTR
SCHEMBL30632044 0.77 PTPN1 (0.39) —
SCHEMBL21766768 0.77 PSMB5 (0.36) IL23RGLP1RSCTR
SCHEMBL21766737 0.74 MAGI3 (0.39) SYK
SCHEMBL30788325 0.74 BACE1 (0.38) —
SCHEMBL11134385 0.74 GNPAT (0.47) —
SCHEMBL18676335 0.73 CTSS (0.39) —
SCHEMBL18381304 0.72 PTPN1 (0.39) —
SCHEMBL12873177 0.72 CALCRL (0.37) GLP1RSCTR
SCHEMBL2742710 0.72 CALCRL (0.37) GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10994017-B2 Nerve labeling compositions and uses thereof AVELAS BIOSCIENCES, INC. (US) 2021-05-04 — — US disclosed
US-20200061200-A1 NERVE LABELING COMPOSITIONS AND USES THEREOF AVELAS ACQUISITION CORPORATION 2020-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200061200-A1 NERVE LABELING COMPOSITIONS AND USES THEREOF GAP43, NGF, PMP22 SYK 3247/4885IL23R 4181/4885GLP1R 2109/4885
US-10994017-B2 Nerve labeling compositions and uses thereof GAP43, NGF, PMP22 SYK 3247/4885IL23R 4181/4885GLP1R 2109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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