Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19051569 | 0.91 | GNPAT (0.40) | GNPATMMETNFPTPN1 | |
| SCHEMBL61371 | 0.90 | ALOX15 (0.42) | GNPATTNFITGB3ITGA2BKDM4E | |
| SCHEMBL6026424 | 0.90 | ALOX15 (0.42) | GNPATTNFITGB3ITGA2BKDM4E | |
| SCHEMBL61370 | 0.90 | ALOX15 (0.42) | GNPATTNFITGB3ITGA2BKDM4E | |
| SCHEMBL19051620 | 0.89 | GNPAT (0.44) | GNPATTNFITGB3ITGA2B | |
| SCHEMBL7162435 | 0.88 | ALOX15 (0.41) | GNPATTNFITGB3ITGA2BKDM4E | |
| SCHEMBL7162439 | 0.88 | ALOX15 (0.41) | GNPATTNFITGB3ITGA2BKDM4E | |
| Water SCHEMBL6933673 | 0.88 | ALOX15 (0.41) | GNPATTNFITGB3ITGA2BKDM4E | |
| Water SCHEMBL8680771 | 0.88 | ALOX15 (0.41) | GNPATTNFITGB3ITGA2BKDM4E | |
| SCHEMBL30632044 | 0.88 | PTPN1 (0.39) | GNPATACEMMEEDNRACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083612-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, Michel (FR) | 1983-07-20 | — | — | EP | disclosed |
| WO-1983000146-A1 | NEW DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PREPARATION THEREOF AND UTILIZATION THEREOF AS DRUGS | FLORK, MICHEL | 1983-01-20 | — | — | WO | disclosed |