Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SPR | P35270 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730627 | 0.85 | SPR (0.49) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL14076464 | 0.82 | TSHR (0.47) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL40921 | 0.82 | TSHR (0.57) | TSHRALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL15478442 | 0.80 | LMNA (0.49) | TSHRSPRALDH1A1LMNA | |
| SCHEMBL13963375 | 0.79 | ALDH1A1 (0.44) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL24535559 | 0.77 | TSHR (0.43) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL17490617 | 0.77 | MEN1 (0.56) | TSHRALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL14076461 | 0.77 | SPR (0.44) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL24607163 | 0.77 | MEN1 (0.56) | TSHRSPRALDH1A1HSD17B10KDM4E | |
| SCHEMBL18098230 | 0.77 | KDM4E (0.46) | TSHRSPRALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268317-B1 | INTEGRIN TARGETING AGENTS AND IN VIVO AND IN VITRO IMAGING METHODS USING THE SAME | VISEN MEDICAL INC (US) | 2020-02-26 | — | — | EP | disclosed |