SCHEMBL21767983

SCHEMBL21767983

ClC1=NN(c2ccccc2)NC(c2ccccc2)=C1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ GLA P06280 2/20 0.35
▸ MAPT P10636 2/20 0.35
▸ TDP1 Q9NUW8 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 3/20 0.31
▸ KMT2A Q03164 3/20 0.31
▸ ALDH1A1 P00352 2/20 0.30
▸ HPGD P15428 2/20 0.30
▸ RXFP1 Q9HBX9 1/20 0.30
▸ APOBEC3G Q9HC16 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25292012 0.93 CYP1A2 (0.35) KDM4ENPC1RAB9AGLAMAPT
SCHEMBL7259734 0.82 LMNA (0.41) KDM4ENPC1RAB9AGLAMAPT
SCHEMBL25292308 0.81 CYP1A2 (0.41) KDM4ENPC1RAB9AMAPTTDP1
SCHEMBL6634795 0.80 MEN1 (0.33) KDM4ENPC1RAB9AGLAMAPT
SCHEMBL25295105 0.80 CYP2A6 (0.42) NPC1RAB9ASMN1; SMN2LMNAALDH1A1
SCHEMBL22685703 0.79 KDM4E (0.35) KDM4ENPC1RAB9AGLAMAPT
SCHEMBL15453282 0.79 KDM4E (0.39) KDM4EGLAL3MBTL1SMN1; SMN2LMNA
SCHEMBL2117781 0.79 CYP1A2 (0.31) L3MBTL1SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL2250599 0.77 KMT2A (0.34) KDM4EGLAMAPTSMN1; SMN2LMNA
SCHEMBL25291740 0.76 CYP1A2 (0.44) KDM4EGLAL3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12520720-B2 Heterocyclic compound and organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-01-06 — — US disclosed
EP-3617202-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2025-11-05 — — EP disclosed
CN-110862378-B Heterocyclic compound and organic light-emitting device 三星电子株式会社 2024-11-15 — — CN disclosed
CN-117940412-A Fluoranthene derivative, light-emitting element, and photoelectric conversion element 东丽先端材料研究开发(中国)有限公司 2024-04-26 — — CN disclosed
WO-2023125801-A1 FLUORANTHENE DERIVATIVE, LIGHT-EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT 东丽先端材料研究开发(中国)有限公司 2023-07-06 — — WO disclosed
CN-110590827-B Organic electroluminescent compound and application thereof 武汉天马微电子有限公司 2023-02-03 — — CN disclosed
US-20200083458-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KP) 2020-03-12 — — US disclosed
CN-110862378-A Heterocyclic compound and organic light-emitting device 三星电子株式会社 2020-03-06 — — CN disclosed
EP-3617202-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2020-03-04 — — EP disclosed
CN-110590827-A Organic electroluminescent compound and application thereof 上海天马有机发光显示技术有限公司 2019-12-20 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200083458-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CRY1, CYP1A1, CYP1B1 KDM4E 2486/4885NPC1 3276/4885RAB9A 2619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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