SCHEMBL22685703

SCHEMBL22685703

BrC1=NN(c2ccccc2)NC(c2ccccc2)=C1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 2/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ RXFP1 Q9HBX9 1/20 0.30
▸ APOBEC3G Q9HC16 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ HPGD P15428 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7259734 0.82 LMNA (0.41) KDM4ENPC1GLAMAPTMAPK1
SCHEMBL21767983 0.79 KDM4E (0.35) KDM4ENPC1GLAMAPTMAPK1
SCHEMBL17063458 0.79 NPC1 (0.39) KDM4ENPC1MAPTMAPK1RAB9A
SCHEMBL11207466 0.79 ALDH1A1 (0.31) KDM4ENPC1MAPK1RAB9ALMNA
SCHEMBL2161417 0.78 ALDH1A1 (0.41) KDM4ENPC1MAPTMAPK1RAB9A
SCHEMBL25292308 0.74 CYP1A2 (0.41) KDM4ENPC1MAPTMAPK1RAB9A
SCHEMBL25292012 0.73 CYP1A2 (0.35) KDM4ENPC1GLAMAPTMAPK1
SCHEMBL25295105 0.73 CYP2A6 (0.42) NPC1RAB9ALMNASMN1; SMN2ALDH1A1
SCHEMBL15453282 0.72 KDM4E (0.39) KDM4EGLAL3MBTL1LMNASMN1; SMN2
SCHEMBL25291740 0.70 CYP1A2 (0.44) KDM4EGLAL3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 — — US disclosed
CN-110028459-B Compound, display panel and display device 武汉天马微电子有限公司 2023-04-18 — — CN disclosed
US-20200388764-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-12-10 — — US disclosed
US-20200373493-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200373493-A1 COMPOUND, DISPLAY PANEL AND DISPLAY APPARATUS C1S, CDK20, CEP170 KDM4E 3873/4885NPC1 3305/4885GLA 2945/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 KDM4E 3873/4885NPC1 3305/4885GLA 2945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback