SCHEMBL21780087

SCHEMBL21780087

NC/C(=C/F)COc1ccc(C(=O)N2CCc3cc(C(F)(F)F)ccc3C2)cc1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 15/20 0.52
AOC2 O75106 2/20 0.50
MAOB P27338 2/20 0.48
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MAOA P21397 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21768076 0.96 AOC3 (0.51) AOC3AOC2MAOBCA1CA2
SCHEMBL21780142 0.85 AOC2 (0.56) AOC3AOC2MAOBCA1CA2
SCHEMBL21780132 0.85 AOC2 (0.56) AOC3AOC2MAOBCA1CA2
SCHEMBL21780085 0.85 CA1 (0.40) AOC3MAOBCA1CA2CA7
Trifluoroacetic Acid SCHEMBL21768159 0.84 AOC3 (0.52) AOC3AOC2MAOBCA1CA2
Trifluoroacetic Acid SCHEMBL21768084 0.84 AOC3 (0.52) AOC3AOC2MAOBCA1CA2
Trifluoroacetic Acid SCHEMBL30089516 0.84 AOC3 (0.52) AOC3AOC2MAOBCA1CA2
Trifluoroacetic Acid SCHEMBL21768080 0.84 AOC3 (0.52) AOC3AOC2MAOBCA1CA2
SCHEMBL21780048 0.79 AOC2 (0.52) AOC3AOC2MAOBMAOA
Trifluoroacetic Acid SCHEMBL21768119 0.78 AOC2 (0.48) AOC3AOC2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617186-A1 FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-03-04 EP disclosed