Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 17/20 | 0.49 |
| ▸ | PPARA | Q07869 | 17/20 | 0.49 |
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217822 | 0.90 | PPARA (0.40) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL217526 | 0.90 | PPARA (0.51) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL217949 | 0.90 | PPARA (0.49) | PPARDPPARAPPARG | |
| SCHEMBL217208 | 0.89 | PPARA (0.42) | PPARDPPARAPPARG | |
| SCHEMBL217328 | 0.85 | PPARA (0.58) | PPARDPPARAPPARG | |
| SCHEMBL217859 | 0.84 | PPARA (0.39) | PPARDPPARAPPARG | |
| SCHEMBL217972 | 0.83 | PPARA (0.46) | PPARDPPARAPPARG | |
| SCHEMBL217585 | 0.82 | PPARA (0.50) | PPARDPPARAPPARG | |
| SCHEMBL4737326 | 0.82 | PPARA (0.58) | PPARDPPARAPPARG | |
| SCHEMBL217635 | 0.81 | HSD17B1 (0.47) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079722-B1 | SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONE AND 3-PHENYL-1-(PHENYLFURANYL)PROPAN-1-ONE DERIVATIVES, AND PREPARATION AND USE OF SAME | GENFIT (FR) | 2015-06-17 | — | — | EP | claimed |
| US-8088819-B2 | Derivatives of substituted 3-phenyl-1-(phenylthienyl)propan-1-ones and of 3-phenyl-1-(phenylfuranyl) propan-1-ones, preparation and use | GENFIT (FR) | 2012-01-03 | — | — | US | claimed |
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | GENFIT (FR) | 2010-02-04 | — | — | US | claimed |
| EP-2079722-B1 | SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONE AND 3-PHENYL-1-(PHENYLFURANYL)PROPAN-1-ONE DERIVATIVES, AND PREPARATION AND USE OF SAME | GENFIT (FR) | 2015-06-17 | — | — | EP | disclosed |
| US-8088819-B2 | Derivatives of substituted 3-phenyl-1-(phenylthienyl)propan-1-ones and of 3-phenyl-1-(phenylfuranyl) propan-1-ones, preparation and use | GENFIT (FR) | 2012-01-03 | — | — | US | disclosed |
| US-8088819-B2 | Derivatives of substituted 3-phenyl-1-(phenylthienyl)propan-1-ones and of 3-phenyl-1-(phenylfuranyl) propan-1-ones, preparation and use | GENFIT (FR) | 2012-01-03 | — | — | US | disclosed |
| US-8088819-B2 | Derivatives of substituted 3-phenyl-1-(phenylthienyl)propan-1-ones and of 3-phenyl-1-(phenylfuranyl) propan-1-ones, preparation and use | GENFIT (FR) | 2012-01-03 | — | — | US | disclosed |
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | GENFIT (FR) | 2010-02-04 | — | — | US | disclosed |
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | GENFIT (FR) | 2010-02-04 | — | — | US | disclosed |
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | GENFIT (FR) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029745-A1 | DERIVATIVES OF SUBSTITUTED 3-PHENYL-1-(PHENYLTHIENYL)PROPAN-1-ONES AND OF 3-PHENYL-1-(PHENYLFURANYL) PROPAN-1-ONES, PREPARATION AND USE | TPP1, NAT1, PGC | PPARD 4/4885PPARA 16/4885PPARG 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.