Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769400 | 0.95 | NPSR1 (0.45) | KDM4ELMNAALDH1A1NPSR1NOD2 | |
| SCHEMBL21769463 | 0.91 | KDM4E (0.44) | KDM4ELMNAALDH1A1NPSR1NOD2 | |
| SCHEMBL21769477 | 0.91 | MAPT (0.47) | KDM4ELMNAALDH1A1NPSR1CACNA1G | |
| SCHEMBL21440788 | 0.90 | ALDH1A1 (0.48) | KDM4EALDH1A1NPSR1CACNA1GSMN1; SMN2 | |
| SCHEMBL21769398 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1NPSR1CACNA1GSMN1; SMN2 | |
| SCHEMBL21769529 | 0.86 | NPSR1 (0.40) | KDM4ELMNAALDH1A1NPSR1NOD2 | |
| SCHEMBL21769245 | 0.86 | MAPT (0.46) | ALDH1A1NPSR1CACNA1GSMN1; SMN2USP2 | |
| SCHEMBL21769479 | 0.86 | NPSR1 (0.46) | KDM4ELMNAALDH1A1NPSR1CACNA1G | |
| SCHEMBL21769228 | 0.84 | NPSR1 (0.49) | ALDH1A1NPSR1CACNA1GSMN1; SMN2USP2 | |
| SCHEMBL21769231 | 0.82 | DRD3 (0.54) | KDM4EALDH1A1NPSR1SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200064334-A1 | Dock Derived Compound against Laminin Receptor (37 LR) and Uses thereof | ILK, LRRC47, RPL37 | KDM4E 3638/4885LMNA 174/4885ALDH1A1 1721/4885 |
| US-11022604-B2 | Dock derived compound against laminin receptor (37 LR) and uses thereof | ILK, LRRC47, RPL37 | KDM4E 3638/4885LMNA 174/4885ALDH1A1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.