RPL37

Large ribosomal subunit protein eL37 (60S rib · P61927 · RPL37 on Sugi Atlas →

3,531 patent compounds predicted against RPL37, 1,820 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL5500526	0.41	4/20
SCHEMBL5500532	0.41	4/20
SCHEMBL5503310	0.41	4/20
SCHEMBL11844361	0.35	4/20
SCHEMBL2000440	0.39	3/20
SCHEMBL8219903	0.36	3/20
SCHEMBL11627320	0.34	3/20
SCHEMBL10271044	0.55	2/20
SCHEMBL6394396	0.47	2/20
N-Methylpiperidine (SCHEMBL11205373)	0.42	2/20
Bicarbonate (SCHEMBL9058396)	0.42	2/20
SCHEMBL4960293	0.41	2/20
SCHEMBL4961968	0.40	2/20
SCHEMBL6686992	0.40	2/20
SCHEMBL9429122	0.38	2/20
Chloramphenicol (SCHEMBL10796001)	1.00	1/20
Geneticin (SCHEMBL15596)	0.93	1/20
Geneticin (SCHEMBL5006573)	0.93	1/20
Geneticin (SCHEMBL9920496)	0.93	1/20
Chloramphenicol (SCHEMBL16111)	0.90	1/20

Clinical trials — most relevant to RPL37 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes	PHASE4	UNKNOWN
Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From Real World	PHASE4	UNKNOWN
COMPARING TWO PROTOCOLS FOR FINAL OOCYTE MATURATION IN POOR RESPONDERS UNDERGOING GnRH-ANTAGONIST ICSI CYCLES	PHASE3	UNKNOWN
Antiviral Activity and Safety of 3 Different Doses of Mifepristone in Hepatitis C Infected Patients	PHASE2	COMPLETED
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Targeting Endoplasmic Reticulum Stress in Human Hypertension	PHASE1/PHASE2	RECRUITING
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients	PHASE1/PHASE2	COMPLETED
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors	PHASE2	RECRUITING
Safety and Pharmacology of SNX-5422 Plus Carboplatin and Paclitaxel in Subjects With Solid Tumors	PHASE1	COMPLETED
Study of Oral CNF2024 (BIIB021) in Advanced Solid Tumors	PHASE1	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors	PHASE1	COMPLETED
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery	PHASE1	COMPLETED
RibOSE - Glucose and Resistance Exercise Training	nan	COMPLETED
Effect of Branched Chain Amino Acids on Muscle	nan	COMPLETED
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy	nan	UNKNOWN
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Role of Sorcin and Annexin A3 in Breast Cancer Patients	nan	UNKNOWN
Impact of Mutations in Aminoacyl tRNA Synthetases on Protein Translation and Cellular Stress	nan	WITHDRAWN
miR-155 Expression in Episodic and Chronic Migraine	nan	UNKNOWN
Comparative of Plasma Proteomics & Metabolomics in Coronary Artery Disease: Obstructive,Non-Obstructive, & No Lesions	nan	RECRUITING
Somatosensory Modulation of Salivary Gene Expression and Oral Feeding in Preterm Infants	nan	COMPLETED
Perfusion-Induced Hyperthermia for Metastatic Carcinoma	nan	COMPLETED
LncRNA Nicotinamide Nucleotide Transhydrogenase-Antisense RNA1 NNT-AS1 in CRC	nan	COMPLETED
Quantification of GADD34 Expression in RA	nan	COMPLETED
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia	nan	COMPLETED
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a RPL37 binder may also engage these)

Protein	Name	Similarity
P79244	—	1.000	P79244 →
Q90YT1	—	1.000	Q90YT1 →
P61928	—	1.000	P61928 →
U3KPD5	—	1.000	U3KPD5 →
Q9D823	—	1.000	Q9D823 →
O44125	—	1.000	O44125 →
Q9VXX8	—	1.000	Q9VXX8 →
Q962S7	—	1.000	Q962S7 →
P49166	—	1.000	P49166 →
P59289	—	0.999	P59289 →
P51402	—	0.999	P51402 →
Q9W1U6	—	0.998	Q9W1U6 →
Q8U0P5	—	0.998	Q8U0P5 →
Q6BPF6	—	0.997	Q6BPF6 →
Q9C0T1	—	0.997	Q9C0T1 →
Q8LEM8	—	0.997	Q8LEM8 →
Q2NF48	—	0.997	Q2NF48 →
Q9P836	—	0.997	Q9P836 →
P62004	—	0.996	P62004 →
P62005	—	0.996	P62005 →
Q97ZQ1	—	0.996	Q97ZQ1 →
P49622	—	0.995	P49622 →
Q9YEQ4	—	0.995	Q9YEQ4 →
Q6LY46	—	0.995	Q6LY46 →
Q43292	—	0.995	Q43292 →
Q4JAZ9	—	0.995	Q4JAZ9 →
P0DJ24	—	0.995	P0DJ24 →
P05733	—	0.994	P05733 →
Q5JIE1	—	0.994	Q5JIE1 →
P62885	—	0.994	P62885 →