Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.48 |
| ▸ | CSNK1G2 | P78368 | 5/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 5/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24092763 | 0.84 | TYMS (0.45) | CSNK1DCSNK1G2CSNK1A1GSK3BAPP | |
| SCHEMBL20961864 | 0.82 | LMNA (0.61) | MAPTPOLBRAB9ALMNASMN1; SMN2 | |
| SCHEMBL12109509 | 0.81 | ALDH1A1 (0.58) | APPMAPTEGFRPOLBRAB9A | |
| SCHEMBL12331846 | 0.81 | ADORA2A (0.64) | CSNK1DCSNK1G2CSNK1A1GSK3BADORA2A | |
| SCHEMBL19216416 | 0.80 | PLAU (0.56) | APPMAPTEGFRPOLBALDH1A1 | |
| SCHEMBL2146355 | 0.80 | ALDH1A1 (0.56) | MAPTADORA2AEGFRRAB9ALMNA | |
| SCHEMBL25749256 | 0.80 | MEN1 (0.54) | APPMAPTPOLBRAB9AHTT | |
| SCHEMBL28376156 | 0.80 | ALDH1A1 (0.61) | MAPTPOLBRAB9AGFERSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20291496 | 0.80 | ADORA2A (0.62) | CSNK1DCSNK1G2CSNK1A1GSK3BADORA2A | |
| SCHEMBL9979367 | 0.80 | ALPL (0.51) | ADORA2AKDRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613743-A1 | PROCESSES FOR THE PREPARATION OF 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE DERIVATIVES | Intellikine, LLC (US) | 2020-02-26 | — | — | EP | disclosed |