Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | MET | P08581 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
| ▸ | MERTK | Q12866 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200868 | 0.80 | ALDH1A1 (0.40) | AXLMETPOLBALDH1A1KMT2A | |
| SCHEMBL21785275 | 0.79 | CDC25A (0.40) | CDC25ACDC25CAXLMETPTGS2 | |
| SCHEMBL10396790 | 0.79 | PTGS2 (0.40) | CDC25ACDC25CAXLMETALDH1A1 | |
| SCHEMBL24878448 | 0.78 | CDC25A (0.40) | CDC25ACDC25CAXLMETALDH1A1 | |
| SCHEMBL15334264 | 0.75 | AXL (0.49) | CDC25ACDC25CAXLMETKDM4E | |
| SCHEMBL21776508 | 0.74 | AXL (0.51) | CDC25ACDC25CAXLMETPTGS1 | |
| Hydrochloric Acid SCHEMBL29812561 | 0.73 | AXL (0.50) | CDC25ACDC25CAXLMETPTGS1 | |
| SCHEMBL15334268 | 0.72 | KDM4E (0.49) | AXLMETALDH1A1KMT2AKDM4E | |
| SCHEMBL23147692 | 0.72 | CDC25A (0.39) | CDC25ACDC25CAXLMETKDM4E | |
| SCHEMBL23882496 | 0.71 | AXL (0.48) | CDC25ACDC25CAXLMETALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038460-A1 | NOVEL QUINOLINE DERIVATIVE INHIBITOR | 南京药捷安康生物科技有限公司 | 2020-02-27 | — | — | WO | disclosed |